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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'affd550b24ad110978857b2c7721e39ac8d35d1103a5df3c988349aca0571e46' 
  AND token = 'oWYJLpxR+EurnY8up29HO4gbi7wWuL23zAQS8vdDCd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}