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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26ac79243f3ed3b2ce70a722cd0d2b98202b3467238ee9bde734d38067f2579a' 
  AND token = 'dIAhOMlvk11BbsF+8YY5SGY5atrMih0+tfGdqBy4nv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}