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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43e4cb7aef0dcca84558529cb48840a7e0b529c41d1f828af52479474915e24' 
  AND token = 'WMpX9TDC/ohoQ9cxQQn6a785uO7IYTxJsDc2//AeEx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}