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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '614e441e71eb2f1811dc0a7bc4fa2afc04e3297bc6243cb6e78bf3d8962da41d' 
  AND token = 'dGGIZgCpGxaG1QI6Tnj0BHxsSol0zZcwMDjGE2RW8WA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}