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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aa8c44454b73256393e25fc5280e173818cc65fc83fca243a6576fa50af7de5' 
  AND token = 'Rs8WLkrqrxG1iUtegMfGWNm2jHoeRVhnMa8urUsbw2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}