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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dc5f909b8acfba0c52cc0241c0a71bb4e264c48c3a121ddb5a0bf0b1a386974' 
  AND token = 'rnqVsSeWpRiIfn8lWNG3DUl4Xbo4w86NqohRBTdfuKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}