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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '922f568849d33c7c123d9e2253398adf66d1dab100dfff8916d6a4bedd3e2cbb' 
  AND token = 'CQxN0iAVfmPysrCYwX9Y88XhEBD9Yp5ctyyzhUQtl/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}