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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1ea2051f984e8b699a52a30faa03a631857d02057e645144e2545eb27ba4cfc' 
  AND token = 'OA2GnHwJxCGAqexjlyYGo2BTwcsrHzB+mj9oI4sTOTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}