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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '536e2822080b0579377edbca3b1a161dde9d8f2d40c522225795844da09fe0fe' 
  AND token = 'G5+1kgvUY5IwCOErHe36tmvoGe2c/4EYFCF0tdMsmoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}