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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bdd8c6de13b3fa98113376063111a617d2a1f9b2388d3679c85cb74365d03f2' 
  AND token = 'xX3xse0r/71Cq7IyBRq31FpU145fbknJOqyHkwq7Uf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}