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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7653a82fdf84a9dd3ab4f84c6e47496f59b1531587f977ccf3b959591c3cf555' 
  AND token = 'bzGFcRYZ81v6/8i8RPeUFsRvlHL5lma57clirAsWN0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}