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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '268b36d099ad4f5ccf365980a70652dc43e50a76cdf50d7f05c0859e516d12c7' 
  AND token = '4HII4yAZC34MNJyawJ2EJBbNhiC0pAz62WchPnOr7/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}