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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18bfc6a3863aa05b127d67f1b0cc70308ae18bf139404daa2d655d26c0a4858f' 
  AND token = 'H0W2cvYY9RPzco6uAKFB0E99jcOrucltbMGCC5zGAq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}