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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a593c5c667aa1f3b2eeb546afb5ad9fa65e33a39cbe0feed463d630b806da6e' 
  AND token = 'FDMiMIk9l/tVVDnCGPjbTPcbnNm2/x/69GwWlqbeTKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}