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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453676c4f148b33a5a5293a057ade662290985a93d0113c6a5d7776e3988079e' 
  AND token = '1EmJZF+wevAszHZauN9RYA3ZL3o36izKKuTrGCK6NKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}