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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9e22c62421cb6e3a62f8076ce482499f3e829ef3573e7b6fb96f267b57afe7f' 
  AND token = 'w2KGZ2/kC6E+Pb/UGZzrcl9WdTT7n2KqJAXvvglL//A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}