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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6802f8e52f962d15f81910d9c9f8708b17bc8c10ede3b9fc42d8fb4255f7008' 
  AND token = 'x0WsZ7L6CrQ94uOar5yscaEJ9Gur1r6FG0S+1rgnVC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}