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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b28c84b48f2006672f5522f51d7fc728bca6f667a3db33fa1a6e6f6b78bb461e' 
  AND token = 'l1FCJ3xskQrbi0Xccta2p0yU/BrZfGJvoWebRo7R+SY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}