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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14a0d3f77d2bbc3cb7f2587bf0cd414af78d27ec2f5819fe352ddf0e73a4c196' 
  AND token = 'k5XNnZ5b+QXXUH6QHPDo8LnfRElIm4q8kKpO6bkR9aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}