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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49289eb427209b9608bb28fef4c8d023211faa8598e6cfd787541eb262e7c6d' 
  AND token = 'iq6JQYGubGnpdH7NQlcDaQF9AJ2AmK6Dhhh4E3ha84k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}