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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '121239df226eaf88f625b500309b5b750b3266f3ac20085743815b18e31becec' 
  AND token = 'bd8Wdp7fD0mxqCgH8YsydrT/a7q9DNJ5IGNsswf8bao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}