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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e00fa0f653779ac159a038cce0bd9db9ae818e3ffd9f14c430019ac35d8d9ad' 
  AND token = '2LfwYh7Qidb46nP9vxg+dGncA+CyVbDd8iSXYsNpfqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}