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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e10cc9026c018cabfa711af8f6b68323c9f04e9a435d6f9874283eb1e5d8853' 
  AND token = '6kxU+Ys5qtVsMRkwrgIKSf51c3UIeOkrIHGDopsIOF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}