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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e3d60ac486090d5f57dfb7620a9df0a99f76e00262aedc3d299e47eeb370825' 
  AND token = '7R59nUbLdFwiPjpt+yOr1RTOiUlmOWyuD+eeboNaaCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}