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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7535cfe2eba4dd4509f823cd65a39c177eb8f6641d1532a471ca6f380ca23c72' 
  AND token = 'N1MOOkACuIg0/rXuINwrbdGFFBWPDxlOLmL94MCrdtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}