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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6360eb678e8bb58365dd850a72b4a35ee306aa8c436d4b06f367c7027f7cc5e' 
  AND token = 'f7Z5R57TJbjCGxO+R3ixgCgyzO84NOvz9iEnX4hO4Vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}