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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c129cd8e96f4e0d80eeb2dd53282851b5982d972a3be72d791f87760fe56330f' 
  AND token = '6a2WAvquc9VflAGZx4fM7pKUVWkI+4Bo5lqAFVgE3Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}