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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a25dc45eada5a276e713073df89bde7b95c0d449b8d3fa434d7c03ae38f98a9' 
  AND token = 'jtwRvL28R4B6WdryZFaG2c0JDSqhfpecXJAv38ddZ9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}