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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4489134c2f4d2c75c7f231f171c24bb0e8b551033ce3f4caa88128b5ae759fae' 
  AND token = 'dt/OA7Z+L6SDzdQ8EkyEjOIPjlSyuYp7Kiygafe7PEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}