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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d6cc8a05921ea7b29c9e3a013cdfc4dc80021da6a080cd00f24cd9c49b40c92' 
  AND token = 'oHJueJ7/JDbprHgQqtKmmtruEoIcsM222NuH9Y6zg1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}