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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1653131b7c0dc21cb1e3d2a3ec36be6b6fd6571336de745b309dddf4c715562b' 
  AND token = '8H0qMSsu9btVa5D2w+i1QUDVhq8lJ6Iw+CkT2sCWvMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}