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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c9d6091de90ec305023a0e25cad7b408028f4cf30004fc0aa2bc23dafeb3d59' 
  AND token = 'hZWHQtn+xPjMI8XBoXAL8kj6MZS+hcTOS/5vNqG7fC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}