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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b442635ba62f55e037b9fb9e556a87def86a3f12a74f6c27ce1752229733aac' 
  AND token = 'abXX27XjpAAWfFUzTr1QnpjsGQzZ2a77iPnSAldsmoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}