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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03b91de259f98e5ef16adc25f827eb36908b6ead11ec09d01807cf744c9a66a8' 
  AND token = 'QoI4s35NLxWk9vraDopxuACA7ZAypFVmC3OOfZx10PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}