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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6b185c8f4e2bb35ea49e4a27d41366b4aae6363b064752ab87df20ba2729063' 
  AND token = 'vkZq5SUpKfC4BiyDScsUXBAX7EWP6nmhCoyQ4zCkrw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}