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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f7cefa9e1d688923f249d7c93f0b2971d7a9b6ac716041b6865208082a5378' 
  AND token = 'fuLls2QuzRr4EbqOx7ktUqiA6hh1DWlJfU3UEMCPCrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}