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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c87d25102170df082b7fe2677e6b1287e81f80ed8d99c0b3ccd78568dc3b862b' 
  AND token = 'PJy5JjiMIITRrwJGH/7/JbOErAO81Ya0q56yTJcZueE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}