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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd29bad2f066acde4738e5011186bfbe46a935628fe8cbc58fe8b448755d61bd5' 
  AND token = 'zoZ7fgb3C5dh3ZKUy7vAtHCktJ05BZ5dxRx8Ef4tUjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}