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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a712cd3d2734cbfc11c3c8d3d2603532ac972d62a63f60bb10d15e14d351cb' 
  AND token = '8dcTPndMZrwiC9u6ufB3PlJRHI3OXfxTUdCKdR8OXc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}