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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74d45870be004c22527542b1466119b7de6f4529c13554b853c210cff2f1927a' 
  AND token = 'e8/RrWFXT+mhe/BVMWfYhLj7jU8BRTkbSLYXRYVX0B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}