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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e118a034b229bd5e55379f049defeaa9ebdba5082a85f4d06d6657c3b1e97225' 
  AND token = 'aV9OXvl1Z4dyH7BLy0XdW41o2R8me/zyEJQEN0vDs/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}