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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a19f27aa2723732cd50c2506c3d2812531c26745174b96ca0044f7e597751bd6' 
  AND token = 'hDeQUHJrR/cnuqhVOwChnyX3EOoYoYd2e8p5RK2FsAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}