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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b7525efa555df84162c915f740bb52a67f37e411a0f4b09dc8dd813d39eb74' 
  AND token = 'PbxSLqrhMYZDNTCz/IftndyVDuU67t1gjhkEUc5AehU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}