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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1404644d598b9a1ecec9652ee5c39fc3183fc04fc3085a33db436869cc3be731' 
  AND token = '8j3Gkp5ZY3IC1P5AjDZL3jRHIG0Evdao1zPJP0Ee9AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}