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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427198abbc8c3a37fcff0f048f64d8381d86008c1e66d7026041ed0713c9ee1f' 
  AND token = 'md6Eu1zhz+eHicxQE9uzGhE/fe1X7RoNtUO2NJ3ofq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}