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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5af352dfbe65e8f18e5a7b57bd7a6361c053c5896fd59cd0285b0a4642c7128a' 
  AND token = 'gNR4hYc97xrflq46QUgSfNDbzX+mRSGDzqrWE3sLDrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}