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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f9668866bb47cf1ee48d9b23103d34cc8f48580eaea9c5be1737cf06fb851c' 
  AND token = 'n3DqlKWup6gyFhM42C0zxUyaKKvJ2sJ1hedfuWxJgUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}