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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05fabf837817cd4ff157defab373eb06521c3fea11b5113616bf3aa1fb345787' 
  AND token = 'zwTmISY+aoq3SxGQqyBF4n6V5Af6ij+X7xilS6W2Miw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}