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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd18c2b9e46693a7eb109666f122d3b1d9461e17cfae47015309dd055b04efefb' 
  AND token = '5D8kuJYPQ01npb25e11hJshhUcd55K4RRU5xfZVfg2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}