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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa16d195c91e997f995f9b8a08ff85e272c3cddd0632375d0bde30f11af2c67f' 
  AND token = 'ZXfojbfrh8RBdMHlMRjeesC4+Q3VFldkd6Gm10Ajv68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}